<?xml version='1.0' encoding='UTF-8'?><?xml-stylesheet href="http://www.blogger.com/styles/atom.css" type="text/css"?><feed xmlns='http://www.w3.org/2005/Atom' xmlns:openSearch='http://a9.com/-/spec/opensearchrss/1.0/' xmlns:georss='http://www.georss.org/georss' xmlns:gd='http://schemas.google.com/g/2005' xmlns:thr='http://purl.org/syndication/thread/1.0'><id>tag:blogger.com,1999:blog-4723837718792687849</id><updated>2011-04-21T20:50:23.412-07:00</updated><category term='cooking'/><category term='formula cooking'/><category term='spaghetti'/><category term='steak'/><title type='text'>Genetics Made Easy</title><subtitle type='html'></subtitle><link rel='http://schemas.google.com/g/2005#feed' type='application/atom+xml' href='http://geneticsmadeeasy.blogspot.com/feeds/posts/default'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/4723837718792687849/posts/default?max-results=100'/><link rel='alternate' type='text/html' href='http://geneticsmadeeasy.blogspot.com/'/><link rel='hub' href='http://pubsubhubbub.appspot.com/'/><author><name>Bob Parmelee</name><uri>http://www.blogger.com/profile/15296742935976269840</uri><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='32' height='24' src='http://bp0.blogger.com/_VLaGL0JJYAM/R1dsijpNshI/AAAAAAAAAAs/8cNXwrQxbxo/S220/YellowTee_headshot.jpg'/></author><generator version='7.00' uri='http://www.blogger.com'>Blogger</generator><openSearch:totalResults>2</openSearch:totalResults><openSearch:startIndex>1</openSearch:startIndex><openSearch:itemsPerPage>100</openSearch:itemsPerPage><entry><id>tag:blogger.com,1999:blog-4723837718792687849.post-5445294032116987527</id><published>2008-06-08T00:33:00.000-07:00</published><updated>2008-06-08T00:37:37.876-07:00</updated><category scheme='http://www.blogger.com/atom/ns#' term='steak'/><category scheme='http://www.blogger.com/atom/ns#' term='formula cooking'/><category scheme='http://www.blogger.com/atom/ns#' term='spaghetti'/><category scheme='http://www.blogger.com/atom/ns#' term='cooking'/><title type='text'>Which type of cook are you?</title><content type='html'>There are two types of cooks. Those who cook by formula and those who cook by feel. The difference is subtle, but the results are extraordinary. The formula cook is a cook from day one. Anyone can follow a recipe. The second type of cook takes years of practice, some intuition, and a good sense of smell.&lt;br /&gt;&lt;br /&gt;Let’s say you want to cook a steak. The formula says add a pinch of salt and pepper, maybe onion and garlic salt, and maybe Worcestershire Sauce. Or maybe just “steak seasoning.” The cook by formula measures out the ingredients and applies them according to the instructions. The burner is hot, the steak is seasoned, and the cooking begins. The result sometimes is a flavorful piece of shoe leather.&lt;br /&gt;&lt;br /&gt;On the other hand, we have a feel type of cook who recognizes the steak he/she is dealing with is less marbled and tougher than a fast cooking can stand. This cook recognizes tenderizing is required, by the needle or maybe aging, in order to render this particular piece of meat fit for steak. Otherwise, it may be better served with a longer, slower, lower temperature roast style cooking. The difference is in the feel of the meat.&lt;br /&gt;&lt;br /&gt;Another example might be spaghetti. The formula cook assembles all the ingredients: tomatoes (diced), sauce, celery, onion, garlic, mushrooms, fennel (intriguing), pepper, hamburger, and (also intriguing) sausage. The browning begins. First the meats, spiced according to formula. You strain out the meat into another pot, and then add the parsley, oregano, basil, rosemary, veggies and bay leaf to the juice. Things simmer. Finally, after awhile the combination of meats and vegetables occurs, and voilà, the meal is done, but falls flat.&lt;br /&gt;&lt;br /&gt;You know you did everything right. The measurements were correct. You didn’t skip any ingredients, so what went wrong?&lt;br /&gt;&lt;br /&gt;Well the answers are various. The usual culprit is stale spice. Any spice, (my rule) on the shelf for over six months needs to be doubled to have the same effect as a recipe amount. Also, a subtle but potent difference could be the timing of the addition of “colorful” spices. If you add herbs too soon, for example, they dissipate before the meal has finished cooking. They may need to be added again to recover their essence. Here is where the seasoned sense of smell plays a key role. If you sniff the pot and it smells mediocre, it tastes mediocre.&lt;br /&gt;&lt;br /&gt;Time is of the essence and a good cook is as seasoned as the pot he/she cooks in. Nothing, in my opinion, is as satisfying as a mouth watering, fork tender meal, whether vegetable or animal. The key to achieving the desired result every time is a combination of formula, feel, and a good sense of smell.&lt;div class="blogger-post-footer"&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/4723837718792687849-5445294032116987527?l=geneticsmadeeasy.blogspot.com' alt='' /&gt;&lt;/div&gt;</content><link rel='replies' type='application/atom+xml' href='http://geneticsmadeeasy.blogspot.com/feeds/5445294032116987527/comments/default' title='Post Comments'/><link rel='replies' type='text/html' href='http://www.blogger.com/comment.g?blogID=4723837718792687849&amp;postID=5445294032116987527' title='0 Comments'/><link rel='edit' type='application/atom+xml' href='http://www.blogger.com/feeds/4723837718792687849/posts/default/5445294032116987527'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/4723837718792687849/posts/default/5445294032116987527'/><link rel='alternate' type='text/html' href='http://geneticsmadeeasy.blogspot.com/2008/06/which-type-of-cook-are-you.html' title='Which type of cook are you?'/><author><name>Bob Parmelee</name><uri>http://www.blogger.com/profile/15296742935976269840</uri><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='32' height='24' src='http://bp0.blogger.com/_VLaGL0JJYAM/R1dsijpNshI/AAAAAAAAAAs/8cNXwrQxbxo/S220/YellowTee_headshot.jpg'/></author><thr:total>0</thr:total></entry><entry><id>tag:blogger.com,1999:blog-4723837718792687849.post-654540931229171482</id><published>2007-12-29T15:28:00.000-08:00</published><updated>2007-12-29T15:31:15.042-08:00</updated><title type='text'>Genetics Made Easy (Ha)</title><content type='html'>There has been an enormous amount of progress made since Watson and Crick first discovered the double helix structure of DNA in 1958. The original and deceptively simple version held that genes encoded proteins in our cells. These proteins, in turn, did the work necessary to keep an organism alive. At that time it was thought that only 1.5% of the genome was actually used for this purpose. The other 98.5% of the genome was dubbed “junk DNA” assumed to have been left over from a millennia of mutations during life’s millions of years of evolution on this planet.&lt;br /&gt;     What is amazing , to me at least, is the fact that, as complicated as we humans are, we only have about 2,000 more genes, or about 10% more, than the microscopic roundworm. And the roundworm doesn’t even have a brain!  What we do have in abundance are RNA transcripts which are produced by these genes of ours. It turns out these RNA transcripts do the real work of differentiating us from roundworms. A good analogy would be to picture the building of a garage versus the building of a hospital. The basic materials like dimension lumber, sheet rock, plumbing pipes or wiring and roofing are the same. The tools necessary to assemble these materials, like hammers and nails, saws and screws are the same also. What is different is the complexity of the structure or the blueprints. The construction of a hospital involves the orchestration of hundreds or thousands of rules which specify which materials are used, where they are used, and when. In our cells the RNA transcripts provide the assembly instructions for our body’s blueprints, and when they spring into action.&lt;br /&gt;     Although it took less than a decade to sequence our DNA once the tools were available, it will probable take decades to unravel the regulatory function of our RNA transcripts. The complex interweaving of genes, transcripts, and the regulation each provides has spawned an alphabet soup of anacronyms describing these newly found roles. One thing is certain. The evolution of our understanding of  our genetic coding will get a great deal more complicated before it begins to get sorted out again.&lt;br /&gt;&lt;br /&gt;Bob Parmelee                 Parmsplace.com&lt;div class="blogger-post-footer"&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/4723837718792687849-654540931229171482?l=geneticsmadeeasy.blogspot.com' alt='' /&gt;&lt;/div&gt;</content><link rel='replies' type='application/atom+xml' href='http://geneticsmadeeasy.blogspot.com/feeds/654540931229171482/comments/default' title='Post Comments'/><link rel='replies' type='text/html' href='http://www.blogger.com/comment.g?blogID=4723837718792687849&amp;postID=654540931229171482' title='0 Comments'/><link rel='edit' type='application/atom+xml' href='http://www.blogger.com/feeds/4723837718792687849/posts/default/654540931229171482'/><link rel='self' type='application/atom+xml' href='http://www.blogger.com/feeds/4723837718792687849/posts/default/654540931229171482'/><link rel='alternate' type='text/html' href='http://geneticsmadeeasy.blogspot.com/2007/12/genetics-made-easy-ha.html' title='Genetics Made Easy (Ha)'/><author><name>Bob Parmelee</name><uri>http://www.blogger.com/profile/15296742935976269840</uri><email>noreply@blogger.com</email><gd:image rel='http://schemas.google.com/g/2005#thumbnail' width='32' height='24' src='http://bp0.blogger.com/_VLaGL0JJYAM/R1dsijpNshI/AAAAAAAAAAs/8cNXwrQxbxo/S220/YellowTee_headshot.jpg'/></author><thr:total>0</thr:total></entry></feed>
